Dothiepin: Drug Information

Generic name: Dothiepin

Brand Name: Dosulepine, Prothiaden

Other names: Dopin, Doth, Dothex, Dothitab, Exodep, Pindep

Drug Class: Antidepressant

Dothiepin is an antidepressant drug that is used in the treatment of certain psychiatric disorders such as depressions. It is also known as Dosulepin and works by hindering the reuptake of non -adrenaline in the central nervous system (CNS). It is also known to exhibit anxiolytic properties.

Dosage:

Dothiepin can be taken orally with or without meals. It is essential for you to stick to the dosage prescribed by your doctor and take the medicine at equal intervals everyday. Do not stop taking it abruptly without the consent of your doctor as it may result in worsening your symptoms.

Warning and precautions:

Do not take this drug if you are hypersensitive to it.

This drug is not meant for infants and children.

Do not take this drug if you are recovering from recent MI or have been diagnosed with heart blockage, mania, cardiac arrhythmias, prostrate disease or chronic liver disease.

This drug should not be given to pregnant women.

If you are taking other medicines such as central nervous system (CNS) depressants, you must not take Dothiepin.

You must tell your doctor if you have been diagnosed with or have a history of epilepsy, hypertension, glaucoma or urinary retention before taking this medicine.

Caution and close drug monitoring is required when administering Dothiepin to the elderly.

Tell your doctor if you are lactating prior to taking this medicine.

Do not consume alcohol when on Dothiepin.

Drug Interactions:

Dothiepin can react with various medicines; therefore, it is essential for you to tell your doctor beforehand if you are taking any other prescription or non-prescription drugs. Dothiepin should not be taken with barbiturates as they reduce its antidepressant properties. Do not take this medicine with mono amine oxidase inhibitors (MAOIs), sympathomimetics, narcotics and alcohol.

Side effects of Dothiepin:

Some of the most common side effects of the medication include tachycardia, sexual dysfunction, skin rash, dry mouth, hypertension, cardiac arrhythmias, constipation, drowsiness, tremors and cholestatic jaundice.

Abrupt withdrawal symptoms of Dothiepin include insomnia, irritability and excessive sweating.